Friday, August 23, 2024

30F Lupus Entire history since 2017 along with 2022 AND 2023 EMR discharge summaries

Our first clinical encounter with her was in 5/11/2022 and borrowing from the student's online learning portfolio (who documented the initial encounter at the time here: https://rishithareddy30.blogspot.com/2022/11/30-yrs-old-female.html?m=1


"History of presenting illness:

patient was apparently normal till six years back in 2017 she had generalised body aches and joint pains which involves multiple large joints of which elbow And knee joints  troubled her associated with generalised body aches after multiple hospital visits 
she even noticed hair loss without scarring and oral ulcers then she was diagnosed with autoimmune disorder and initiated on hydroxychloroquine azathioprine wysolone  
she reported that her joint pains and hair loss was not improving  with the above medication she had multiple hospital visits and admissions for joint pains and body aches which bothers her from doing her activities .

Two months back she had pedal edema  two months back she had pedal edema  sudden onset shortness of breath initially on exertion then she was diagnosed with hypertensive emergency admitted and discharged with antihypertensive . patients stopped AZA as advised by doctor  except hyper antihypertensive since yesterday she had shortness of breath initially on exertion which rapidly progressed to sob at rest."

Two more students from the same batch:



2022 EMR discharge summary:

Age/Gender : 31 Years/Female
Address :
Discharge Type: Relieved
Admission Date: 05/11/2022 11:02 PM
Diagnosis
ACUTE CARDIOGENIC PULMONARY EDEMA SECONDARY TO CHRONIC RENAL FAILURE SECONDARY TO ?SLE /LUPUS NEPHRITIS
SEIZURES SECONDARY TO ?CNS VASCULITIS /?UREMIC


Case History and Clinical Findings


PT CAME WITH C/O SOB SINCE MORNING ON 5/11/22 C/O VOMITINGS 2 EPISODES
K/C/O SLE SINCE 2017 ON REGULAR MEDICATION K/C/O HTN SINCE 1 MONTH ON REGULAR MEDICATION N/K/C/O DM,ASTHMA,EPILEPSY,TB
PATIENT WAS APPARENTLY ASYMPTOMATIC 6 YEARS BACK
IN 2017 SHE HAD GENERALISED BODYACHES AND JOINT PAINS WHICH INVOLVED MULTIPLE LARGE JOINTS OF WHICH ELBOW AND KNEE JOINT ACHES TROUBLED HER ASSOSCIATED WITH GENERALISED BODY ACHES
AFTER MULTIPLE HOSPITAL VISITS SHE EVEN NOTICED HAIR LOSS WITHOUT SCARRING AND ORAL ULCERS
THEN SHE WAS DIAGNOSED WITHAUTOIMMUNE DISORDER SLE AND INITIATED ON HCQ
,AZATHIOPRINE AND WYSOLONE .
SHE REPORTED THAT HER JOINT PAINS AND HAIRLOSS WAS NOT IMPROVING WITH ABOVE MEDICATION
 

2 MONTHS BACK SHE HAD PEDAL EDEMA AND SUDDEN ONSET OF SHORTNESS OF BREATH INITIALLY ON EXERTION THEN WORSENED TO EVEN AT REST


SHE WAS DIAGNOSED WITH HYPERTENSIVE EMERGENCY ADMITED AND DISCHARGED WITH ANTIHYPERTENSIVES

SINCE 10 DAYS PATIENT STOPPED TAKING ALL HER MEDICATIONS EXCEPT ANTIHYPERTENSIVES

SINCE YESTERDAY[4/11/22] SHE HAD SHORTNESS INITIALLY ON EXERTION WHICH RAPIDLY PROGRESSED TO SOB AT REST

NO SMALL JOINTS PAINS NO COLOUR CHANGE /PARAESTHESIAS OF FINGERS ON EXPOSURE TO COLD

PT HAD 1 EPISODE OF INVOLUNTARY MOVEMENTS INITIALLY STARTED LEFT HAND FOLLOWED BY TOTAL BODY WITH IMPAIRED CONSCIOUSNESS
NO TONGUE BITE ,NO INVOLUNTARY MICTURITION /DEFECATION 


ON EXAMINATION


PT IS CONSCIOUS COHERENT COOPERATIVE ON PRESENTATION

 VITALS

BP 220/140 MMHG PR 134 BPM
RR 36CPM SPO2 52 ON RA
GRBS 236 MG /DL
GENERAL PHYSICAL EXAMINATION PALLOR +
FLAT NAILS
NON SCARRING ALOPECIA
HYPERPIGMENTED DISCOID RASHES ON FACE PERIAURAL BLACK DISCOLORATION OF ORAL MUCOSA AND PALATE MILD PEDAL EDEMA
CVS
NO RAISED JVP S1S2+
NO MURMURS RS
BAE +
DIFFUSE INSPIRATORY AND EXPIRATORY CREPTS +
 

P/A SOFT NON TENDER MILD DISTENDED UMBILICUS INVERTED NO ORGANOMEGALY CNS
HMF INTACT E4V5M6 PUPILS NSRL NO FND
LAST SEIZURES 4/11/22 COURSE IN HOSPITAL
4 SESSIONS OF DIALYSIS DONE OPHTHA REFERAL ON 5/11/22
IMPRESSION- NO CHANGES ON FUNDUS EXAMINATION DVL REFERAL ON 7/11/22
DIAGNOSIS-SYSTEMIC LUPUS ERYTHEMATOSUS +CICATRICIAL ALOPECIA TREATMENT-TACROS OINT 0,03% L/A /OD FOR 2 WEEKS
PHOTO BAN AQUA GEL L/A [9AM-12PM-3PM] RENAL BIOPSY DONE ON 12/11/22
Investigation
CBP HB TC N L E M B PLT SMEAR RFT UR CR UA CA+2 P NA+ K+ CL- HIV HBSAG HCV MDCT SCAN BRAIN PLAIN
IMPRESSION-
F/S/O HYPERTENSIVE ENCEPHALOPATHY /POSTERIOR REVERSIBLE ENCEPHALOPATHY[PRES]
Treatment Given(Enter only Generic Name)
INJ LEVIPIL 500 MG /IV/TID
INJ NTG 50 MG IN 50 ML NS @5ML/HR INC /DEC TO MAINTAIN SBP <160 MMHG[STOPPED ON 07/11/22]
INJ LASIX 40 MG/IV/BD INJ HAI S/C ACC TO GRBS
TAB .NICARDIA RETARD 20 MG /PO/QID TAB OROFER XT PO/OD
TAB HCQ 200 MG PO/BD
TAB METXL 50 MG PO/BD TAB TELMA 40 MG PO/OD
TAB WYSOLONE 20 MG /PO/OD TAB HYDRALAZINE 12.5 MG PO/TID TAB PCM 650 MG/PO/QID
TAB DEPINE 5MG /PO/QID FLUID AND SALT RESTRICTION
Advice at Discharge
TAB LEVIPIL 500 MG PO/'BD TAB LASIX 40 MG PO/BD
TAB .NICARDIA RETARD 20 MG /PO/QID TAB OROFER XT PO/OD
TAB METXL 50 MG PO/BD TAB TELMA 40 MG PO/OD
TAB WYSOLONE 20 MG /PO/OD TAB PCM 650 MG/PO/QID
TAB ULTRACET 1/2 TAB PO/QID[1/2-1/2-1/2-1/2] FLUID AND SALT RESTRICTION
When to Obtain Urgent Care
IN CASE OF ANY EMERGENCY IMMEDIATELY CONTACT YOUR CONSULTANT DOCTOR OR ATTEND EMERGENCY DEPARTMENT.
Preventive Care
AVOID SELF MEDICATION WITHOUT DOCTORS ADVICE,DONOT MISS MEDICATIONS. In case
of Emergency or to speak to your treating FACULTY or For Appointments, Please Contact:  For Treatment Enquiries Patient/Attendent Declaration : - The medicines prescribed and the advice regarding preventive aspects of care ,when and how to obtain urgent care have been explained to me in my own language
SIGNATURE OF PATIENT /ATTENDER SIGNATURE OF PG/INTERNEE SIGNATURE OF ADMINISTRATOR SIGNATURE OF FACULTY
Discharge Date Date:14/11/22 Ward:NEPHRO WARD
 

2023 discharge summary : 

Date of admission: 06/02/2023 02:37 PM

Diagnosis

ACUTE KIDNEY INJURY ON CHRONIC KIDNEY DISEASE [LUPUS NEPHRITIS STAGE 1V/V] SECONDARY TO ACUTE GASTROENTERITIS [ RESOLVED ]
WITH HYPERKALEMIA [ RESOLVED ]
WITH ? ANEMIA OF CHRONIC INFLAMMATION WITH ? ANEMIA INDUCED HEART FAILURE WITH ? ACUTE PULMONARY EDEMA [RESOLVED]


Case History and Clinical Findings


CHIEF COMPLAINTS :
C/O VOMITING AND LOOSE STOOLS SINCE 3 DAYS HOPI :
PT WAS APPRENTLY ASYMPTOMATIC 3 DAYS AGO THEN SHE DEVELOPED LOOSE STOOLS 3-4 EPISODES / DAY , WATERY CONSISTENCY , NOT ASSOCIATED WITH FEVER , PAIN ABDOMEN
C/O VOMITINGS SINCE 3 DAYS 2-3 EPISODES PER DAY CONTAINED FOOD PARTICLES INITIALLY THEN HAD YELLOWISH COLOR VOMITINGS , NON FOUL SMELLING , NON BLOOD STAINED
 

K/C/O SLE WITH LUPUS NEPHRITIS SINCE 2 MONTHS AND IS ON TAB HCQ 200MG IS ON RABEPRAZOLE + DOMPRIDONE 7AM
T.OROFER XT PO/OD 8AM T.SHELCAL 500MG PO/OD 8AM
T.SODIUMBICARBONATE 500MG PO/BD 2PM AND 8PM T.NICARDIA 20MG PO/TID 8AM-2PM-8PM T.NEPHROSAVE PO/OD 2PM
PROBIOTICS
N/K/C/O DM , ASTHMA , EPILEPSY , CAD , CVA , THYROID DISORDERS K/C/O HTN SINCE 3 MONTHS
NO PAST SURGICAL HISTORY MENSTRUAL CYCLE :
IRREGULAR SINCE 2 MONTHS LMP - 25TH DECEMBER 2022 


O/E:
PT. IS C/C/C
NO PALLOR,ICTERUS,CYANOSIS,CLUBBING,LYMPHEDENOPATHY,PEDAL EDEMA TEMP : 98.2F
BP-180/110MMHG PR-131BPM
RR-24CPM RBS-118MG/DL
CVS-S1S2+,NO MURMURS RA-BAE+,NVBS
P/A-SOFT, TENDERNESS AROUND UMBLICUS , BOWEL SOUNDS HEARD CNS-NO FND
OPTHALMOLOGY OPINION WAS TAKEN I/V/O HYPERTENSIVE RETINOPATHY CHANGES AND NO HYPERTENSIVE CHANGES WERE NOTED
GYNECOLOGY OPINION WAS TAKEN I/V/O AMENORRHOEA SINCE 3 MONTHS AND ENT OPINION WAS TAKEN I/V/O DYSPHAGIA AND WAS DIAGNOSED ODYNOPHAGIA SECONDARY TO GASTRITIS
BLOOD TRANSFUSION OF 1 PRBC WAS DONE ON 13/2/23 IV/O LOW HEMOGLOBIN NEPHROLOGY OPINION WAS TAKEN I/V/O OF RASIED SERUM CREATINE AND UREA LEVELS AND WAS ADVICED HEMODIALYSIS

HEMODIALYSIS WAS DONE ON 16/2/23 AND 17/2/23
Investigation
USG ABDOMEN AND PELVIS ON 06/2/23
B/L RAISED ECHOGENECITY IN BOTH KIDNEYS MILD ASCITIS
USG ABDOMEN AND PELVIS ON 9/2/23
GB WALL EDEMA NOTED MEASURING 8MM
MILD RIGHT PLEURAL EFFUSION , MINIMAL LEFT PLEURAL EFFUSION IVC DIAMETER MAX 18MM MIN 16MM
DILATED HEPATIC VEINS NOTED MINIMAL PERICARDIAL EFFUSION FEATURES SUGGESTIVE OF SEROSITIS HEMOGRAM
HB - 4.4-6.7-6.1-5.9-6.0-6.3-8.5-8.9-7.6-7.6-7.8 MG/DL
TLC - 5500-3400-5960-6980-6190-8700-12200-11400-6500-7900- 8300 CELLS/MM3 PLT - 90K - 80K- 96K-1.40L-1.58L-1.1L-1.5L-1.82L-2.10L -2.4L

Treatment Given(Enter only Generic Name)
IV FLUIDS NS AT 100ML/HR NEB WITH DUOLIN 6TH HRLY INJ PAN 40MG IV/OD
INJ ZOFER 4MG IV/SOS INJ LASIX 40MG IV/BD
INJ METROGYL 500MG IV /TID
INJ METHYLPREDNISOLONE 1GM IV/OD INJ NTG 2CC IV GIVEN
TAB NICARDIA 10MG PO/SOS TAB CLINIDIPINE 10MG PO/BD TAB WYSOLONE 40MG PO/OD TAB SPOROLAC DS PO/BD TAB HCQ 200MG PO/OD
TAB AZATHIOPRINE 50MG PO/OD
SYP SUCRALFATE 10ML TID BEFORE FOOD TAB MET XL 25MG PO/OD
 

Advice at Discharge
TAB NICARDIA 30MG AT 8AM , 20MG AT 2PM , 30MG AT 8PM TAB HCQ 200MG PO/OD
TAB MET-XL 25MG PO/OD
TAB AZATHIPRINE 50MG PO/OD
TAB WYSOLONE 30MG/PO OD 20MG AT 8AM 10MG AT 6PM TAB PAN 40MG PO/OD
TAB ZOFER 4MG PO/SOS TAB LASIX 40MG PO/TID
SYP SUCRALFATE 10ML PO/TID BEFORE MEALS
Follow Up
REVIEW SOS OR AFTER 1 WEEK TO GENERAL MEDICINE OPD
When to Obtain Urgent Care
IN CASE OF ANY EMERGENCY IMMEDIATELY CONTACT YOUR CONSULTANT DOCTOR OR ATTEND EMERGENCY DEPARTMENT.
Preventive Care
AVOID SELF MEDICATION WITHOUT DOCTORS ADVICE,DONOT MISS MEDICATIONS. In case
of Emergency or to speak to your treating FACULTY or For Appointments, Please Contact:  For Treatment Enquiries Patient/Attendent Declaration : - The medicines prescribed and the advice regarding preventive aspects of care ,when and how to obtain urgent care have been explained to me in my own language
SIGNATURE OF PATIENT /ATTENDER SIGNATURE OF PG/INTERNEE SIGNATURE OF ADMINISTRATOR SIGNATURE OF FACULTY
Discharge Date Date:14/2/23 Ward:AMC
Unit: 1

Finally this month presented in the meeting circulated here:



INTEGRATED MEET CASE PRESENTATION
DR.JYOTHULA HARIPRIYA
FINAL YEAR POSTGRADUATE
DEPARTMENT OF GENERAL MEDICINE


CHIEF COMPLAINTS
A 30 years old woman , resident of , ... by occupation  came with  chief complaints of:
Swelling of both lower limbs since 3 days.
Decreased urine output since 1 day.
Shortness of breath since 1 day.

 
HISTORY OF PRESENT ILLNESS
Patient was apparently asymptomatic 3 days back and then she had swelling of both lower limbs,which is insidious in onset, gradually progressive ,pitting type, initially started around ankle and extended till knee associated with facial puffiness and dry cough more on lying down position.
Decreased urine output since 1day.
Shortness of breath since 1 day ,insidious in onset ,gradually progressive, from MMRC grade 2 to grade 4[worsened since 30 minutes].
Sudden onset of shortness of breath since 30minutes.


HISTORY OF PRESENT ILLNESS
Orthopnoea and PND present.
No h/o fever, Cold, Cough.
No h/o pain abdomen, Vomiting, Loose stools.
No h/o chest pain,palpitations.
No history of burning micturition


PAST HISTORY
TIMELINE OF EVENTS





PAST HISTORY
K/C/O Hypertension since 7 months and was on medication, Tab. Nicardia 30mg PO TID
K/C/O SLE since 6 years used Rx for 5 years and stopped.
Renal biopsy done on 12/11/2022 - Diagnosed with Lupus Nephritis [restarted  on Rx].
Not a k/c/o Diabetes mellitus, Thyroid, Coronary artery disease, Cerebrovascular accident.
PERSONAL HISTORY
Mixed diet
Appetite decreased.
Bowel habits regular
Decresed urine output since 1 day.
Sleep adequate.
No allergies
Addictions: Nil.
GENERAL EXAMINATION
Patient is consious and coherent at the time of presentation.
Poorly built and nourished.
Pallor present
Edema +[Both lower limbs]
Buccal pad of fat lost.
JVP: Raised



GENERAL EXAMINATION
Non scarring alopecia present
Hyper pigmented discoid rashes over the face
Black discoloration of oral mucosa and palate.
No icterus, Cyanosis, Clubbing, Koilonychia, Lymphadenopathy.

CLINICAL IMAGES





GENERAL EXAMINATION
Pulse Rate:131 Beats per minute, Regular, normal volume.
Blood Pressure:180/110mmHg,Right Arm, Supine position.
Respiratory Rate:30 Cycles Per minute
Temperature:98.2F
GRBS: 98mg/dL.
SPO2:-82% on room air
94% on NIV

SYSTEMIC EXAMINATION
RESPIRATORY SYSTEM :
Inspection:
Chest is elliptical shaped, Bilaterally symmetrical.
Trachea is central.
Movements are equal on both sides.
No scars, sinuses or visible pulsation.
SYSTEMIC EXAMINATION
RESPIRATORY SYSTEM:
Palpation:
All inspectory  findings are confirmed :Trachea is central.
Apex beat felt in left 6th Intercostal space lateral to mid clavicular line.
Vocal fremitus felt equally in all areas
SYSTEMIC EXAMINATION
RESPIRATORY SYSTEM:
Percussion:
All areas are resonant on percussion  
Auscultation:
Bilateral air entry present
Normal vesicular breath sounds heard.
Fine end inspiratory and expiratory crepitations heard all over the chest[more in bilateral basal regions].

SYSTEMIC EXAMINATION
CARDIOVASCULAR SYSTEM:
Elliptical and Bilaterally symmetrical chest
No visible pulsations/engorged veins/scars/sinuses on chest wall.
Apex beat palpable at left 6th Intercostal space lateral to mid clavicular line.
S1 and S2 heard
JVP raised.
No Murmurs,No parasternal heave.
SYSTEMIC EXAMINATION
PER ABDOMEN :
On inspection:
Scaphoid.
Umbilicus inverted.
All quadrants are moving equally with respiration.
No visible pulsations/engorged veins/scars/sinuses.

SYSTEMIC EXAMINATION
Palpation:
Soft and non tender.
No organomegaly.
No  palpable masses.
Percussion:
Tympanic note felt.
Auscultation:
Bowel sounds are heard.
No para aortic briut.


SYSTEMIC EXAMINATION
CENTRAL NERVOUS SYSTEM:
Patient is consious and oriented.
Bilateral pupils Normal size and reactive to light .
Sensory system : Intact
Motor System :Normal
Reflexes: Elicited and normal.
Cranial Nerves: Functional
PROVISIONAL DIAGNOSIS
Acute pulmonary edema secondary to Heart failure.
K/c/o SLE with lupus nephritis and on maintenance hemodialysis.
K/c/o Hypertension.
INVESTIGATIONS




ECG at Admission :
              INVESTIGATIONS
CHEST
X RAY
INVESTIGATIONS
INVESTIGATIONS
ABG
PH      :7.27
PCO2 :19
PO2   :53.5
SO2   :82
HCO3 :7
INVESTIGATIONS
IINVESTIGATIONS
INVESTIGATIONS
KIDNEY BIOPSY
Showed features of chronic renal disease, Tubular injury with significant global glomerulosclerosis, interstitial inflammation and mild arteriosclerosis.
Features suggestive of chronic glomerulonephritis –Lupus nephritis.
2D ECHO
Dilated RA,RV,LA,LV.
Concentric LVH,no RWMA.
IVC Dilated and non collapsing.
Ejection fraction 45%.
Moderate MR,TR.
Mild to moderate AR.
Moderate LV systolic function
Diastolic dysfuntion +.






USG ABDOMEN
FINAL DIAGNOSIS
Acute cardiogenic pulmonary edema
Chronic kidney disease secondary to lupus nephritis [stage iv/v]
Anemia of chronic disease
K/c/o  SLE and Hypertension since 7 months.
TREATMENT
FLUID AND SALT RESTRICTION
TAB.PREDNISOLONE 5MG PO OD
TAB.NICARDIA  30MG/PO//BD
TAB.ARKAMINE 0.1MG/PO/TID
TAB.METAPROLOL 50MG/PO/OD
TAB.SHELCAL CT /PO/OD
TAB.LASIX 40MG/PO/TID
TAB.NODOSIS 500MG/PO/BD


INJ.ERYTHROPOITIN 4000IU/SC/TWICE WEEKLY.
PATIENT WAS ON MAINTANANCE HEMODIALYSIS WITH REGULAR BLOOD TRANSFUSIONS.
COURSE IN THE HOSPITAL
Patient came with complaints of shortness of breath,swelling of both lower limbs and decreased urine output,and clinically and X ray showed features suggestive of flash pulmonary edema , emergency dialysis was done and patient got improved clinically.
FOLLOW UP
Patient is on follow up and is on maintenance hemodialysis .
Last visit on 5-01-2024.
Died outside the hospital.


 THANK  YOU

Sunday, August 18, 2024

PaJR platform methodology: integrating diverse paths of knowing through team based learning and their archival in online learning portfolios: presentation at NCBS Bangalore

Summary: Below are links to videos and slides of our PaJR team presentation at NCBS Bangalore on 14th August, 2024 focusing on our PaJR platform methodology that is largely about integrating diverse paths of knowing through team based learning and their archival in online learning portfolios. This is followed by video links to Prof Sudhir Krishna's presentation of integrating  modern science benches to clinical bedsides where diversity of approaches already abound.


Speaker's list:




Speaker Dr Savanth Reddy's presentation:

Slide:




Speaker notes:


PaJR Online learning Portfolio:

I am Dr.Savanth Reddy  from ... Institute of Medical Sciences, Telangana, India.

Today I would like to introduce about the unique approach followed by the Dept.of General Medicine at our institute which is called  Patient Journey Record System which involves  creation of  an online learning portfolio centered around patient care as we publish  the de-identified patient data as case reports  online at blogspot.com


These case reports are then shared on user-driven forums to facilitate a system of online learning where a concept of Patient as a teacher is emphasized.

This teaching methodology leverages currently available blended learning modalities to create a case based blended learning ecosystem(CBBLE) which is subsequently assessed through peer citations.



There will be offline experiential data capture ,face to face discussion in the demo room and subsequent follow up and family adoption through  PaJR groups which are online components of our blended learning ecosystem.
It is then followed by  an overall weekly logs of academic activities and assessment of students which takes place parallelly.

At the end of each Academic year of UG/PG training  there will be 360 degree formative and summative  assessment  along with the traditional university driven summative assessment .

To be more precise we create  Blog for each individual patient we examine during our clinical rotations and  includes the History,examination videos , lab reports, imaging , differential diagnosis, treatment and the clinical approach used In the patient management.As We use de-identified patient data the privacy of the individual patient is protected .This creates a digital record of the patients we have examined and also we have access to the wide variety of cases even in the future for academic purposes like research and data analysis.We can share the digital record of the clinical condition with  experienced physicians in various renowned institutions and make necessary changes in patient care through discussions which plays a major role in improving the standards of health care and also availability of specialist services in the resource limited areas like the Nalgonda district where our institution is located.To share my personal experience - during my internship I was able to have a sneak peek into the medicine icu cases even though I was posted in other departments which was possible only through the blogs published by the co-interns.
This also stands as an evidence of our commitment and interest towards patient care and is one way of showing our clinical acumen.

Overall it also  helps in the assessment of the students performance through different aspects such as
1)Competence in data capture
2)Competence in Asking questions
3)Competence in finding answers
4)Competence in Communication skills
 throughout the medical school years rather than judging the clinical knowledge based on a 2 hr assessment in the final professional exam.
There will be a review and analysis of anonymised student feedback regarding this teaching delivery method followed by the department .Using this feedback  problem statements will be  identified and solutions are planned accordingly and  students are also involved in making the process efficient.

Hence  there will be Improved Patient care through inputs from various medical professionals, facilitates the Research and data analysis and at the same time patient data privacy is safeguarded.

I would like to conclude the presentation  by re iterating the fact that there may be  different methods we approach in our Patient management but what eventually matters is how it enhances the quality of life in diseased patients.  Thank you.

Link to presentation video:


Speaker Dr Chandana's presentation

Slides:




Presentation video:


Speaker Professor Sudhir Krishna's presentation videos:

Prof Sudhir Krishna takes you on an inspirational journey through Saint John's medical college, MBBS and then a Phd and finally IISc and NCBS, Bangalore with a driving force that fascinates him as to how diverse paths to knowing can be integrated and interconnected!



Prof Sudhir Krishna describes how in order to focus energy on integrative translational research, numerous discussions between basic scientists at NCBS and colleagues from St. John’s medical college campus were conducted in order to understand the perspectives of medical professional around teaching, immediate service and diagnostic innovation needs, affordable therapeutics in contrast to the longer-term perspectives of basic research organizations.


His past work on this:



Thursday, August 15, 2024

20F Lupus clinical complexity EHR deidentified horcrux links to all three admissions and follow up

 Summary: 


This patient was first presented to Prof Michele Meltzer  in Jan 25, 2022 (link: https://youtu.be/X5NBa_0VVUw?feature=shared) in this CPD linked here: https://medicinedepartment.blogspot.com/2022/12/?m=1 and she first presented to the presenters in September 2022 which is recorded in the link below but to summarise it drastically, she had nephrotic glomerular proteinuria, cutaneous vasculitic lesions, CNS vasculitic lessons (investigated for altered cognition) and endocardial and pericardial inflammation (acute heart failure with pericardial effusion)that was attributed to lupus in view of a strong ANA positivity particularly of the ds-dna fraction in ELISA. https://medicinedepartment.blogspot.com/2024/08/first-admission-september-2022-20f-with.html?m=1



Second admission: She again got admitted in December 2022 with headache, altered sensorium and meningeal signs, which was associated with a minor CNS bleed on MRI was later attributed to warfarin (link:

https://drsaicharankulkarni.blogspot.com/2022/12/20f-sle.html?m=1

Her discharge after September 2022 was relatively uneventful on immunosuppressives and while her cardiac and CNS issues were the first to resolve even during admission, her proteinuria also subsided and she gradually withdrew all immunosuppressives in a year with a brief period of iatrogenic Cushing in between. Recently in June 2024, she presented with an ankle flare along with anasarca that also revealed a nephrotic relapse on evaluation of 24 hour urine protein as archived in her PaJR conversations here:https://drsaicharankulkarni.blogspot.com/2022/12/20f-sle.html?m=1

Her 3rd admission recently in July 2024 was for a right hypochondrial pleuritic pain that ultimately revealed a large hydropneumothorax along with multiple lung abscesses. Again this was possibly an iatrogenic result of the high dose immunosuppressives for just a month! There's still a persistent diagnostic uncertainty around the etiology of her lung abscesses and hydropneumothorax as her dry cough persists and her last antibiotics choice was quinolone!https://drsaicharankulkarni.blogspot.com/2022/12/20f-sle.html?m=1








4th admission PaJR update:

[27/08, 14:18]  2020 Pg: Pgs on duty this patient is at OPD please look into this. Preeented with cough

[27/08, 14:34] PaJR moderator: Please ask her to come to ICU

[27/08, 14:54] 2020 Pg: Informed them to meet you in icu sir

[27/08, 15:26] PaJR moderator: Reviewed her in ICU:

Persistent cough

Reduced weight

Anorexia nausea

Will need to be treated for tuberculosis 

We shall repeat chest X-ray, repeat sputum AFB, CBNAAT

[27/08, 15:32] 2020 Pg: Infection causing chronic systemic inflammation sir..?

[27/08, 15:36] PaJR moderator: Her pulmonary issues appear to be tuberculosis as a result of her immunosuppression for Lupus nephritis. They seem to have abruptly stopped her steroids since one month of her discharge and is currently complaining of nausea. Checking her postural BP to add weightage to a possibility of Addison's

[27/08, 15:41] Metacognitist Mover and Shaker1: Addisons mediated by TB or just Glucocorticoid mediated Adrenal Insufficiency?

[27/08, 15:44] PaJR moderator: Yes both are casting their shadows

[27/08, 15:44] PaJR moderator: BP supine 110/70
Standing 90/60

[27/08, 15:45] Metacognitist Mover and Shaker1: This fantastic review should help!

[27/08, 15:47] Metacognitist Mover and Shaker1: I would definitely consider a  9am fasting cortisol at least. Not very expensive and can be useful to diagnose adrenal insufficiency.

Putting her on Hydrocort without this would be quite risky.

[27/08, 15:50] Metacognitist Mover and Shaker1: Quick primer on what steroids can do to the immune system and which organisms can be possible culprits.

[27/08, 16:04] PaJR moderator: We can just restart low physiological dose

[27/08, 16:09] PaJR moderator: @⁨Pushed Communicator 1N22⁩ @⁨Kims PG 2023⁩ Let's start her on Tablet prednisolone 5mg morning (now) and 2.5 mg at night

[27/08, 16:09] Pushed Communicator 1N22: Ok sir




[27/08, 16:12] PaJR moderator: This is her today's chest X-ray and it's remarkably better with disappearance of prior hydropneumothorax and lung abscess shadows with some hint of a residual pleural effusion or thickening. @⁨Pushed Communicator 1N22⁩ please do her chest pleural ultrasound and share the video

[27/08, 16:13] Pushed Communicator 1N22: Okay sir

[27/08, 16:17] Pushed Communicator 1N22: Todays 👆

[27/08, 16:20] PaJR moderator: Let's hope it's all just tuberculosis!

[31/08, 10:29] PaJR moderator: Yesterday for the first time in last one month she didn't cough at night and even now since morning her cough hasn't happened. The only intervention after her admission this Tuesday was restarting her physiological dose of steroids and stopping her previous antibiotics.

She continues to be on the 50 mg azathioprine.

@⁨Pushed Communicator 1N22⁩ @⁨PG 2023⁩ please share her urine for 24 hour protein and creatinine report readied yesterday




[31/08, 10:35] PaJR moderator: Her urine for 24 hour urine protein and creatinine suggests her lupus nephritis is in remission now!

[31/08, 10:39] PaJR moderator: WBC counts since admission has also reduced! Did restarting low dose physiological steroids here have any role!

[31/08, 10:49] PaJR moderator: Just for the record she was also on azathioprine and prednisolone from September 2022 to April 2023

Wednesday, August 14, 2024

First admission September 2022, 20F with Lupus deidentified Horcrux EMR

 September 27, 2022

Intern 2016 batch 

This is an E log book to discuss our patient's de-identified health data shared after taking his guardian's signed informed consent. Here we discuss our individual patient problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. This e-log book also reflects my patient centered online learning portfolio and your valuable comments in comment box are most welcomed 

I have been given this case to solve in an attempt to understand the topic of "Patient clinical data analysis" to develop my competency i reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan

Presentation 

20 year female came to casualty with chief complaints of 

-Hyperpigmented macules since 15 days

-b/l pedal edema since 15 days 

Fever 15 days back

-abdominal distension since 8 days 

-cough(dry) since 7 days 

-Sore throat since 7 days 

-decreased appetite since 7 days 

-decreased urine output since 3 days 

-constipation since 3 days 

-SOB since 5 days

HOPI 

20 year old female came with c/o of b/l pitting type pedal edema extending till knees since 15 days to which she got medical health checkup and prescribed some medication (unknown) then her pedal edema got resolved along with fever she developed Hyperpigmented macules on face later they stopped medications after 2 days she again had a complaints of b/l pedal edema  and fever abdominal distension associated with dry cough and decreased appetite she also has a complaints of DECREASED urine output and constipation since 3 days passing stools once in 3 to 4 days  

N/k/c/o HTN DM THYROID DISORDER CAD EPILEPSY TB












Personal history: 

Mixed diet 

Appetite lost 

Non veg diet 

Bowel and bladder movements are decreased 

Family history :

No significant family history 

O/E :

Pt was c/c/c 

On admission vitals are 

Bp 110/70 

PR 79 

RR 19 

Temp 98.8 


CVS- apex beat replaced laterally palpable thrills and s1 s2 heard mild s3

RS - BAE decreased rt infra scapular crepts present

P/a umblicus is everted

CNS 

MMSE 



Investigations:



30/9/22 




28/09/22


Pleural tap


Cerebral infarcts 














ANA PROFILE





28/9/22
ICU BED NO. 2
B/l pedal edema SOB 
Fever spikes 
O
Pt c/c/c 
Bp - 120/70 
PR - 142 
RR- 29
Temp-99.5
Spo2 - 94 at room air 
A
Post streptococcal glomerulonephritis..??
IGA nephropathy..??
Infective endocarditis..??
P
1)INJ Augmentin 1.2gm iv BD
2)INJ lasix 40mg iv BD
3) NEB Duolin, Budocort 6th hourly
4) INJ neomol 1gm/iv/sos
5) TAB Azithromycin 500mg po bd 
6) Betadine gargles tid

29/9/22

ICU BED NO. 2

B/l pedal edema SOB 

Fever spikes 

O

Pt c/c/c 

Bp - 120/70 

PR - 142 

RR- 29

Temp-99.5

Spo2 - 94 at room air 

A

Post streptococcal glomerulonephritis..??

IGA nephropathy..??

Infective endocarditis..??

P

1)INJ Augmentin 1.2gm iv BD

2)INJ lasix 40mg iv BD

3) NEB Duolin, Budocort 6th hourly

4) INJ neomol 1gm/iv/sos

5) TAB Azithromycin 500mg po bd 

6) Betadine gargles tid 

30/9/22

ICU BED NO. 2

Fever spikes +

Stools not passed 

O

Pt c/c/c 

Bp - 1110/70 

PR - 128

RR- 29

Temp-100.6

Spo2 - 94 at room air 

A

Post streptococcal glomerulonephritis..??

IGA nephropathy..??

Infective endocarditis..??

Polyserositis 2' to SLE

P

1)INJ Augmentin 1.2gm iv BD

2)INJ lasix 40mg iv BD

3) NEB Duolin, Budocort 6th hourly

4) INJ neomol 1gm/iv/sos

5) tab prednisolone 50mg po bd 

6) Betadine gargles tid

7) inj pan 40 mg iv bd 

1/10/22

ICU BED NO. 2

B/l pedal edema subsided

COUGH +

O

Pt c/c/c 

Bp - 110/70 

PR - 125

RR- 29

Temp-98.6

Spo2 - 94 at room air 

A

Falreup of SLE 

infective endocarditis

Drug induced 

P

1)INJ CEFTRIAXONE 1GM IV BD

2)INJ PAN 40 MG IV OD 

3) INJ LASIX 40 MG IV BD 

4) INJ DERIPHYLLIN 100MG IV BD 

5) INJ NEOMOL 1GM IV SOS 

6) TAB PREDNISOLONE 50 MG PO BD

7) NEB BUDECORT 12TH HOURLY



2/10/22

ICU BED NO. 2

Action tremors +

FEVER SPIKES +

O

Pt c/c/c 

Bp - 120/70 

PR - 101

RR- 22

Temp-99.5

Spo2 - 94 at room air 

A

FLARE UP SLE WITH 

LUPUS NEPHRITIS 

CNS LUPUS VASCULITIS 

P

1) Iv fluids NS @30ml/hr 

2) inj methyl Prednisone 750mg in 100ml NS IV OD 

3) INJ. CEFTRIAXONE 1GM IV/BD

4) INJ. PAN 40 MG IV/OD

5) INJ. LASIX 40 MG IV OD

6) INJ.NEOMOL 1GM IV/SOS

7) INJ. DERIPHYLLIN 100MG IV/BD

8) INJ. TRAMADOL 100MG IN 100 ML NS IV/BD 

9) TAB HCQ 200 MG PO/OD

10) TAB. PREDNISOLONE 30MG/PO/BD

11) TAB. DOLO 650 MG PO/TID

12) NEB . BUDECORT P/N 12TH HRLY

13) BP, PR, TEMP, 4TH HRLY CHARTING 


3/10/22

ICU BED NO. 2

B/l pedal edema subsided

COUGH +


Pt c/c/c 

Bp - 110/70 

PR - 125

RR- 29

Temp-98.6

Spo2 - 94 at room air 

A

Falreup of SLE 

LUPUS NEPHRITIS

CNS vasculitis 

P

1)INJ CEFTRIAXONE 1GM IV BD

2)INJ PAN 40 MG IV OD 

3) INJ LASIX 40 MG IV BD 

4) INJ DERIPHYLLIN 100MG IV BD 

5) INJ NEOMOL 1GM IV SOS 

6) TAB PREDNISOLONE 50 MG PO BD

7) NEB BUDECORT 12TH HOURLYSolved 

8) IV fluids NS @50 ml/hr 

9) inj methyl Prednisone IV OD 

10) tab hcq200mg po od 

11) oint t bact l/a bd 

12) neosporin powder for l/a 

4/10/22

ICU BED NO. 2

B/l pedal edema subsided

COUGH +


Pt c/c/c 

Bp - 110/70 

PR - 125

RR- 29

Temp-98.6

Spo2 - 94 at room air 

A

Falreup of SLE 

LUPUS NEPHRITIS

CNS vasculitis 

P

1)INJ CEFTRIAXONE 1GM IV BD

2)INJ PAN 40 MG IV OD 

3) INJ LASIX 40 MG IV BD 

4) INJ DERIPHYLLIN 100MG IV BD 

5) INJ NEOMOL 1GM IV SOS 

6) TAB PREDNISOLONE 50 MG PO BD

7) NEB BUDECORT 12TH HOURLYSolved 

8) IV fluids NS @50 ml/hr 

9) inj methyl Prednisone IV OD 

10) tab hcq200mg po od 

11) oint  t bact l/a bd 

12) neosporin powder for l/a

08/10/22


No fever spikes 


Pt c/c/c 

Bp - 120/90 

PR - 74 

RR- 16

Temp-98

Spo2 - 98 at room air 

A

Falreup of SLE 

LUPUS NEPHRITIS

CNS vasculitis 

P

1)TAB. PAN 40 MG PO OD 

2)TAB. MCQ 200MG/PO/OD

3) TAB PREDNISOLONE 20 MG PO BD

4) TAB. AZORAN 50 MG PO BD 

5) TAB. WARFARIN 5MG PO OD 

6) TAB. WARFARIN 5MG PO OD 

6) SYP. DULPHALAC 15 ML / PO/ TID 

7) OINT - T - BACT L/A BD 

8) CEBHYDRA LOTION L/A BD 

9) NEOSPORIN POWDER L/A







Discussion around the patient
1. Supranuclear bulbar paralysis, a rather more accurate term, is due to an upper motor lesion caused by bilateral disturbance of the corticobulbar tracts. The corticobulbar tracts exert supranuclear control over brainstem motor nuclei and are involved in the muscular movement of the head and neck. They originate from pyramidal cells (Betz cells) in the motor cortex and terminate at cranial nerve nuclei within the brainstem. These nuclei control mastication, deglutition, and speech. Pseudobulbar palsy is characterized by dysarthria, dysphagia, facial and tongue weakness, and emotional lability.[1][2] Any condition which damages bilateral corticobulbar pathways can cause pseudobulbar palsy.
Many pathological conditions can lead to pseudobulbar palsy. These include traumatic brain injury, neoplasm, vascular lesions, metabolic abnormality, or neurological disease. Pseudobulbar palsy is one of the severe complications of cerebrovascular diseases.[2][3]
Rare causes : 
Central pontine myelinolysis
Methotrexate
B/L thalamic infarcts
Neurocysticercosis
PML
Cerebral malaria
Bacterial Endocarditis

Loss of cerebellar modulation (cortico-pontocerebellar pathways) causing emotional dysmetria and disinhibition owing to lesions of corticobulbar volitional pathways are the main pathogenesis explained for pseudobulbar apathy
5. The sequelae reported after viral encephalitis can involve cognitive impairments, motor dysfunction, and epilepsy.Studies of patients who had been diagnosed with viral encephalitis due to HSE have demonstrated sequelae such as speech disorders, memory, and cognitive impairment, personality disorders, and epilepsy (Sellner and Trinka, 2012; Fruchter et al., 2015; Klein et al., 2017). It is vital to notice that the development of epilepsy has been reported 8 years after the onset of the encephalitis, and in nearly 60% of the patients infected with HSV(Sellner and Trinka, 2012; Bonello et al., 2015).









Brisk jaw jerk in pseudobulbar palsy


Glucocorticoid in SLE

"The activation of the non-genomic pathway starts at doses >100 mg/day of prednisone or equivalent. This pathway is especially sensitive to methylprednisolone (MP) and dexamethasone, which have non-genomic effects up to five times more potent than genomic ones [8]. "

We'll change to Methylpred sir?


"The “classical” standard 1 mg/kg/day prednisone dose is not supported by either basic pharmacology or clinical evidence (Figure 1) [19,20]. It is unlikely that anti-inflammatory effects increase significantly after prednisone doses have reached 30–40 mg/day, since such doses already result in a saturation of almost 100% of the genomic pathway [12,19]. Recent data suggest that higher initial doses of prednisone are associated with higher cumulative doses [21] with the well proven result of increasing damage accrual [1,22,23,24,25]. "

Have to I guess.

"The “Rituxilup” schedule, which consisted of rituximab and MP, followed by maintenance treatment with mycophenolate mofetil and no oral steroids, resulted in 72% of patients with LN class III, IV, or V eventually achieving complete remission within a median period of 36 weeks [32]. "

"In 2018, Danza et al. compared the efficacy and rates of infections among patients with several autoimmune conditions, including SLE, treated with MP pulses, for a total dose over three days ≤1500 mg, <1500 to ≤3000 mg and >3000 mg [19]. No differences among the different doses were seen in patients achieving complete response, partial response, or no response. No patients in the ≤1500 mg group suffered infections, vs. 9.1% in the high dose group. " 

Or dexa if there are affordability constraints. 

Unfortunately there aren't many trials with dexa comparing this cheaper alternative with expensive MP



First admission discharge summary

Age/Gender : 21 Years/Female
Address :
Discharge Type: Relieved
Admission Date: 27/09/2022 04:57 PM
Diagnosis
SYSTEMIC LUPUS ERYTHEMATOSUS WITH GLOMERULONEPHRITIC FLARE UP OF LUPUS NEPHRITIS ?CATASTROPHIC APLA SECONDARY TO SLE [LIBMAN SACKS ENDOCARDITIS
,CNS THROMBO EMBOLISM, AND RENAL FAILURE]
Case History and Clinical Findings
20 YR OLD FEMALE CAME ITH C/O B/L PEDAL EDEMA SINCE 15 DAYS HYPERPIGMENTED MACULES SINCE 15 DAYS
FEVER SINCE 15 DAYS
ABDOMINAL DISTENSION SINCE 8 DAYS DRY COUGH SINCE 7 DAYS
SORE THROAT SINCE 7 DAYS DECREASED APPETITE SINCE 7 DAYS SOB SINCE 5 DAYS
DECREASED URINE OUTPUT SINCE 3 DAYS CONSTIPATION SINCE 3 DAYS
HOPI -20 YEAR OLD FEMALE CAME WITH C/O OF B/L PEDAL EDEMA EXTENDING TILL THE KNEES PITTING TYPE SINCE 15DAYS
 

FOR WHICH SHE GOT MEDICAL HEALTH CHECKUP AND PRESCRIBED SOME MEDICATION [UNKNOWN] THEN HER PEDAL EDEMA GOT RESOLVED ALNG WITH FEVER SHE DEVELOPED HYPER PIGMENTED MACULES ON FACE LATER THEY STOPPED MEDICATIONS AFTER 2 DAYS SHE AGAIN HAD A COMPLAINT OF B/L PEDAL EDEMA AND FEVER ABDOMINAL DISTENSION ASSOCIATED WITH DRY COUGH AND DECREASED APPETITE SHE ALSO HAS COMPLAINTS OF DECREASED URINE OUTPUT AND CONSTIPATION SINCE 3 DAYS
PASSING STOOLS ONCE IN 3-4 DAYS N/K/C/O HTN DM THYROID CAD EPILEPSY TB

PERSONAL HISTORY DIET MIXED APPETITE LOST
BOWEL AND BLADDER MOVEMENTS DECREASED


FAMILY HISTORY NOT SIGNIFICNT

O/E-
PT WAS C/C/C
ON ADMISSION VITALS BP 110/70 MMHG
PR-79 BPM RR-19 CPM TEMP -98.8 F
CVS- APEX BEAT DISPLACED LATERALLY PALPABLE THRILL IN MITRAL AREA
LOUD S2 HEARD IN ALL AREAS NO S3 HEARD
PAN SYSTOLIC MURMUR AT MITRAL AREA


RS-
BAE DECREASED
RT INFRA SCAPULAR CREPTS PRESENT P/A-
 

SOFT NON TENDER WITH EMBILICUS NORMAL SHAPE AND INVERTED XIPHI UMBILICAL LENGTH 15 CM
UMBILICO PUBIC LENGTH 12 CM
ON PALPATION NO ORGANOMEGALY


CNS -B/L UPPER LIMB AND LOWER LIMB
HYPER TONIA WITH EXAGERATED DTR ,ABSENT ANKLE REFLEX PATELLAR CLONUS-
RT SIDE 4+
LT SIDE 3+
MOTOR POWER- 4/5 4/5
4/5 4/5


1/10/22
MMSE - DONE ON 1/10/22 ORIENTATION -
ORIENTED TO DAY,MONTH ,SEASON ,DATE -2 FLOOR ,HOSPITAL,DISTRICT,STATE ,COUNTRY-4 RECALL-2/3
ATTENTION AND CALCULATION-3/4 LANGUAGE -2 OBJECTS-2 SENTENCE-1
3 STAGE COMMAND -3 READING CLOSE YOUR EYES WRITING A SENTENCE -0

MODERATE COGNITIVE IMPAIRMENT COURSE IN HOSPITAL
28/09/22-
NEPHRO REFERAL I/V/O ELEVATED RENAL PARAMETERS AND ANASARCA
REFERAL NOTES-LVTS-,OBSTRUCTION -,HEMATURIA-,PYURIA-,YELLOWIS DISCOLORATION-
,NSAID ABUSE -,NATIVE MEDICATION - ADVICED TO CONTINUE THE SAME TREATMENT 28/09/22-
 

PULMO REFERAL I/V/O WHEEZE ,XRAY CHANGES [BL PLEURAL EFFUSION] ADVICED -INJ AUGMENTIN 1.2 GM IV/TID
INJ.LASIX 40 MG IV/BD NED DUOLIN
BUDECORT 6TH HOURLY IMJ NEOMOL 1GM IV/SOS BETADINE GARGLING TAB AZITHROMYCIN

GENERAL SURGERY REFERAL I/V/O BED SORE [1/10/22]
LE- TWO SMALL ULCERS NOTED EITHER SIDE OF INTERGLUTEAL CLEFT MEASURING 1X1 CM EACH
NO ACTIVE DISCHARGE
FLOOR -GRANULATION TISSUE,NO SLOUGH
EDGE SLOPING EDGES NO SURROUNDING INDURATION MARGINS -BLACKISH
ADVICED -TO MAINTAIN HYGEINE AND KEEP THE AREA DRY OINT T BACT FOR LA
NEOSPORIN POWDER FOR LA FREQUENT POSITION CHANGE AIR BED

29/09/22-
ENT REFERRAL WAS TAKEN I/V/O DYSPHONIA REFRAL NOTES-
O/E OF ORAL CAVITY- MUCOSA PALE TONGUE IS COATED
OROPHARYNX-BL GRADE 2 TONSILLAR HYPERTROPHY ,NO CONGESTION NECK-TRACHEA CENTRAL
LARYNGEAL FRAMEWORK NORMAL LARYNGEAL CREPITUS+
NOSE-
EXTERNAL FRAMEWORK NORMAL CAUDAL DISLOCATION-LEFT ANTERIOS MILD DNS -RIGHT
 

B/L NASAL MUCOSA -PALE TURBINATES AND FLOOR -NORMAL ROOMY NASAL CAVITIES
OE EAR-
B/L TYMPANIC MEMBRANE INTACT .,COL+ DIAGNOSIS-DYSPHAGIA UNDER EVALUATION NO ACTIVE ENT INTERVENTION
30/09/22-
REVIEW NEPHRO REFERAL-
USG KUB SHOWING BULKY LT KIDNEY WITH ALTERED ECHOTEXTURE ADVICED TAB AUGMENTIN
TAB PAN 40 MG OD TAB DOLO 650 MG TID 4/10/22-
DVL REFERAL I/V/O HYPERPIGMENTED MACULES NOTED OVER CHEEKS AND FOREHEAD
,NOSE ,CHIN EAR LOBULE ,RETROAURICULAR REGION [CONCHA SPARED], BOTH FOREARMS,BACK,UPPER CHEST
ORAL CAVITY- N
MULTIPLE HYPERPIGMENTED MACULES NOTED OVER BOTH THE PALMS DIAGNOSIS -POST INFLAMMATORY HYPERPIGMENTATION
ADVICED -CEBHYDRA LOTION LA/BD
REVIEW ENT REFERAL I/V/O DYSPHONIA [13/10/22]
ADVICED TO CONTINUE MEDICATION AS ADVICED BY PHYSICIAN WAIT AND WATCH
FOLLOWED BY SPEECH THERAPY


01/10/2022-
20 F WITH ANASRCA BL PEDAL EDEMA ,PLEURAL EFFUSION ,AND PERICARDIAL EFFUSION - RESOLVING
+RASH HEALED +FEVER
SKIN- HEALED RASHES +PAINLESS EMBOLI LIKE LESIONS [JANEWAY LESIONS] PT APPEARS COMFORTABLE
FEVER SPIKES PERSIST -FEVER CHART ANALYSIS-SEPTIC PTTERN ACTION TREMOR+B/L
 

REDUCTION IN TACHYCARDIA[HR 148->112] LIDLAG
HEALING BEDSORE ON BACK [BUTTOCK AREA]


ON 02/10/22-
ANA PROFILE -ANTI dsDNA +++
ANTI HISTONE ,ANTINUCLEOSOME,ANTI KU AG++
MRI BRAIN- MULTIPLE HYPERINTENSITIES IN BRAIN PARENCHYMA F/S/O-VASCULITIS? USG ABDOMEN -MODERATE ASCITES

SLE DAI SCORE-30 POINTS S/O ACTIVE DISEASE


ON 3/10/22-
TACHYPNEA AND TACHYCARDIA SUBSIDED ACTION TREMOR DECREASED

0N 4/10/22
INJ UNFRACTIONATED HEPARIN 5000IU /IV/STAT
FOLLOWED BY INJ UNFRACTIONATED HEPARIN 5000 IU /SC/QID FOR 3 DAYS[GIVEN FOR 3 DAYS [TILL 6//10/22]]
TAB WARFARIN 5MG /PO/OD IS STARTED


TAB LASIX 40MG PO/BD STARTED ON 12/10/22


BLOOD TRANSFUSION WAS DONE ON 13/10/22
ONE PINT OF A+VE BLOOD WAS TRANSFUSED AFTER DOING THE BLOOD GROUPING AND TYPING AND CROSS MATCHING
TRANSFUSION STARTED AT 7;30 PM AND WAS COMPLETED BY 11;20 PM
HALF AND HOURLY MONITORING OF VITALS WAS DONE DURING THE PROCESS OF TRANSFUSION
PRE TRANSFUSION VITALS AND POST TRANSFUSION VITALS WERE MONITORED,PT WAS STABLE AND NO CHILLS,RIGORS,FEVER,MYALGIA DURING THE TRANSFUSION
 

Investigation
USG IMPRESSION[28/09/2022] MODERATE PERICARDIAL EFFUSION BILATERAL PLEURAL EFFUSION GROSS ASCITES

MRI BRAIN PLAIN WITH CSPINE SCREENING[ON 3/10/22] IMPRESSION-
DIFFUSE CEREBRAL AND CEREBELLAR ATROPHY
MULTIPLE SMALL ACUTE INFARCTS IN BOTH CEREBRAL HEMISPHERES-EMBOLIC SCREENING OF CERVICAL AND DORSAL SPINE APPEARS NORMAL
Treatment Given(Enter only Generic Name)
1] INJ AUGUMENTIN 1.2 GM IV/BD FOR 2 DAYS
2] INJ LASIX 40 MG IV/BD FOR 9 DAYS
3] NEB WITH DUOLIN BUDECORT
4] INJ NEOMOL 1GM IV/SOS
5] TAB AZITHROMYCIN 500 MG PO/OD FOR 2 DAYS
6] BETADINE GARGLES /TID
7] INJ DERIPHYLLINE 100 MG IV /BD FOR 7 DAYS
8] TAB PREDNISOLONE 50 MG PO/BD FOR 3 DAYS[STARTED ON 29/9/22 TO 1/10/22] TAB PREDNISOLONE 30 MG PO/BD FOR 1 DAY[STARTED ON 2/10/22 ]
TAB PREDNISOLONE 20 MG PO/BD FOR 11 DAYS[STARTED ON 3/10/22 ] 9]INJ PAN 40 MG IV/OD
10] INJ CEFTRIOXONE 1 GM IV/BD FOR 7 DAYS
11] INJ TRAMADOL 1 AMP IN 100 ML NA/IV/BD
12] INJ METHYL PREDNISOLONE 750 MG IN 100 ML NS/IV /OD FOR 3 DAYS[2/10/22 TO 4/10/22]
13] TAB HCQ 200 MG PO/OD[STARTED ON 2/10/22]
14] TAB DOLO 650 MG PO/TID
15] OINT T BACT FOR LA /BD
16] NEOSPORIN POWDER FOR LA
17] TAB AZORAN 50 MG PO/BD
18] SYP DULPHALAC 15 ML PO/TID
19] INJ UNFRATIONATED HEPARIN 5000 IU/SC/QID FOR 3 DAYS
20] TAB WARFARIN 5MG /PO/OD
 

21] CEBHYDRA LOTION LA /BD
Advice at Discharge
1] TAB HCQ 200 MG PER ORAL ONCE DAILY
2] TAB PREDNISOLONE 20 MG PER ORAL TWICE DAILY
3] TAB AZORAN 50 MG PER ORAL TWICE DAILY
4] TAB LASIX 40 MG PER ORAL TWICE DAILY
5] SYP SUCRALFATE 10 MLTHRICE DAILY
6] SYP DULPHLAC 15 ML PER ORAL THRICE DAILY
7] OINT TBACT LOCAL APPLICATION TWICE DAILY
8] CEBHYDRA LOTION LOCAL APPLICATION TWICE DAILY
9] NEOSPORIN LOCAL APPLICATION
Follow Up
REVIEW TO GM OPD ON TUESDAYS OR SOS
When to Obtain Urgent Care
IN CASE OF ANY EMERGENCY IMMEDIATELY CONTACT YOUR CONSULTANT DOCTOR OR ATTEND EMERGENCY DEPARTMENT.
Preventive Care
AVOID SELF MEDICATION WITHOUT DOCTORS ADVICE,DONOT MISS MEDICATIONS. In case
of Emergency or to speak to your treating FACULTY or For Appointments, Please Contact: For Treatment Enquiries Patient/Attendent Declaration : - The medicines prescribed and the advice regarding preventive aspects of care ,when and how to obtain urgent care have been explained to me in my own language
SIGNATURE OF PATIENT /ATTENDER SIGNATURE OF PG/INTERNEE SIGNATURE OF ADMINISTRATOR SIGNATURE OF FACULTY
Discharge Date Date:13/10/2022 Ward:AMC Unit:GM 2